DNA Chemistry and Sequencing

There are two major research efforts in this division. One effort is to use high-throughput DNA sequencing and analysis technology for whole genome analysis and for mutation scanning and detection (DNA Sequencing). The other effort is to use chemical science and engineering approaches to study biological problems (Chemical Biology), in particular the design and synthesis of novel molecular tags for biological labeling and imaging, and developing new technologies to study problems in genomics. Platforms include massive parallel chip based DNA sequencing, novel approach for using mass spectroscopy to sequence DNA, and the combination of energy transfer dyes and combinatorial chemistry for multiplex biological target detection.